Mass General Brigham May 23 2025 Q: How would you summarize your study for a lay audience? Our study investigated the role of astrocytes, an abundant cell type in the brain, in regulating an immune response against glioblastoma (GBM)-a highly aggressive brain cancer. We found a subset of astrocytes that limits the immune response and can be targeted with therapeutics. Q: What question were you investigating? GBM is a brain cancer that has remained untreatable for decades. Immunotherapies that