Getty Head coach Deion Sanders of the Colorado Buffaloes looks on before the game against TCU Horned Frogs at Amon G. Carter Stadium on October 4, 2025 in Fort Worth, Texas. J ust days after undergoing surgery, Deion Sanders led the Colorado Buffaloes to the team’s first ranked upset win in more than two years, defeating the #22 Iowa State Cyclones 24-17 in Boulder.  After a very disappointing start to Sanders’ first season without Hiesman winner Travis Hunter and son Shedeur Sanders , the win