Dickkopf 3 protein drives radiation-induced fibrosis and chronic skin damage

Ana Maria Rus

Ludwig-Maximilians-Universitaet Muenchen (LMU) Feb 3 2026 The protein Dickkopf 3 plays a key role in the development of radiation-induced fibroses - and could be a promising target for novel therapies. Radiotherapy is one of the main treatment forms for cancer. Among its most common side effects is skin damage, right up to chronic inflammations and fibroses. At present, such long-term damage can only be treated symptomatically and leads to thickened, painful, or sensitive skin for months to

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