‘Rogue’ DNA rings identified as drivers of aggressive brain cancer
Ana Maria Rus
Queen Mary University of London Sep 9 2025 An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes – known as extrachromosomal DNA, or ecDNA – can drive the growth of a large proportion of glioblastomas, the most common and aggressive adult brain cancer. The discovery could open the door to much-needed new approaches to diagnose glioblastoma early, track its progress and treat it more effectively. The findings, published today in Cancer
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