Osaka Metropolitan University Sep 13 2025 Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce the risk of this disease. Aldehyde dehydrogenase 2 (ALDH2) is an important enzyme that detoxifies harmful aldehydes produced in the body. While it is best known for metabolizing acetaldehyde –an aldehyde increased by drinking– it