Aging-US Jun 12 2025 A new research paper was published in  Aging  ( Aging-US ) Volume 17, Issue 5, on May 3, 2025, titled "APOE genotype and biological age impact inter-omic associations related to bioenergetics." In this study, led by first author Dylan Ellis and corresponding author Noa Rappaport from the Institute for Systems Biology, researchers discovered that different versions of the  APOE  gene-particularly ε2 and ε4-are linked to metabolic patterns associated with aging and Alzheimer'