Education Over the last few years, the popularity of glucagon-like peptide-1 receptor agonists (GLP-1) used for weight loss has greatly increased. Type 2 diabetes medications like Ozempic and Mounjaro are sometimes prescribed off label for weight loss, while Wegovy and Zepbound are approved for the treatment of obesity. Industry researchers estimate that while about 12% of United States citizens have used a GLP-1 medication for weight loss, 54% of adults who have taken GLP-1s say it was