VIB Jun 14 2025 Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered how a unique interaction between two cellular compartments, namely the endoplasmic reticulum (ER) and mitochondria, can act as a central ignition point for ferroptosis, a form of cell death driven by lipid oxidation and iron. In a study published in Nature Cell Biology , the team of Professor Patrizia Agostinis highlights the role of ER-mitochondria contact sites (EMCSs) in setting off a cascade that leads