Those who are looking to remove permanent marker stains just need a simple bathroom item to make it disappear. Permanent marker stains can be nearly impossible to get rid of - as its name so aptly tells us. However, some cleaning gurus have shared their fool-proof method to get rid of the pesky marks. All it takes is a simple bathroom item that you can pick up at any supermarket or pharmacy - toothpaste. You can remove permanent marker stains with toothpaste by rubbing it in a circular motion