Shimon Sakaguchi: Regulatory T cells for Immune Tolerance: Discovery and Clinical Prospects Mary Brunkow: FoxP3/Scurfin: A Key Driver of Peripheral Immune Tolerance Fred Ramsdell: Translating Basic Science to Therapeutic Opportunities: the Treg Example The 2025 Nobel Prize in Physiology or Medicine was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance”. Live stream terms of use: https://www.nobelprize.org/ceremony/