By Vijay Kumar Malesu Reviewed by Susha Cheriyedath, M.Sc. Oct 12 2025 By confirming cognitive impairment before ordering amyloid blood tests, this two-step approach cuts false positives, streamlines referrals, and moves Alzheimer’s diagnosis closer to everyday clinics. Study: Primary care detection of Alzheimer’s disease using a self-administered digital cognitive test and blood biomarkers . Image Credit: Orawan Pattarawimonchai / Shutterstock In a recent study published in the journal  Nature