Science China Press Jan 23 2025 Acute myeloid leukaemia (AML) is mainly characterized by an increase in the number of myeloid cells in the bone marrow and a decrease in mature cells, accounting for 28% of leukaemia cases, with a five-year survival rate of only 30.5%. More recently, quantitative proteomics analyses uncovered the heterogeneity of Western AML patients at the protein and phosphorylation modification levels, However, there is still a lack of drug sensitivity integrated with a more