Chemotherapy may trigger inflammatory response that fuels bladder cancer resistance

Taiwan

Houston Methodist Jul 16 2025 Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to treatment, according to new research from scientists at Houston Methodist. The findings are highlighted in "Caspase-1–dependent pyroptosis converts αSMA+CAFs into collagen-III high iCAFs to fuel chemoresistantcancer stem cells," which was recently published in Science Advances . The researchers examined why

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