Harvard Medical School Mar 14 2025 Artificial intelligence can transform medicine in a myriad of ways, including its promise to act as a trusted diagnostic aide to busy clinicians. Over the past two years, proprietary AI models, also known as closed-source models, have excelled at solving hard-to-crack medical cases that require complex clinical reasoning. Notably, these closed-source AI models have outperformed open-source ones, so-called because their source code is publicly available and can