European Society of Gastrointestinal Endoscopy May 15 2026 A comparative study, presented at ESGE Days 2026, has found that endoscopic sleeve gastroplasty (ESG) is associated with significantly greater short-term weight loss than oral semaglutide in adults with obesity. The retrospective cohort study included 150 patients treated in routine clinical practice and evaluated outcomes at six months. Patients undergoing ESG achieved a mean total body weight loss of 12.7 %, compared with 8.7 % in