Nearly 500,000 people are diagnosed with Lyme disease each year in the U.S. For about 75% of them , the first sign will be a skin lesion that appears one to four weeks after being bitten by an infected deer tick. But it might not look how you’d imagine: Only 20% of these lesions take on the classic bull’s-eye appearance commonly associated with Lyme. Other early symptoms of Lyme disease mimic what you might experience with the flu: a fever, chills, muscle aches, and swollen lymph nodes. Within