Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

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ECOG-ACRIN Cancer Research Group Oct 21 2025 A new cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) shows that a drug that utilizes the body's immune system to target and eliminate cancer cells appeared to reduce the risk of distant metastases for an aggressive form of skin cancer when given immediately after surgery, but did not significantly reduce the overall risk of recurrence, which was a co-primary endpoint of the trial. The randomized phase 3 STAMP trial (EA6174)

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