Education According to the European Institute of Women’s Health , each year about 25 million people around the world experience menopause — a time where the female reproductive period ends. Hormone replacement therapy (HRT) is a treatment sometimes prescribed to women going through menopause to help ease the condition’s symptoms . HRT may include individual or combinations of the hormones estrogen and progesterone , depending on a person’s needs. HRT is available in a variety of forms,