Baylor College of Medicine Sep 16 2025 Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, Stanford University School of Medicine and collaborating institutions provide new insights into how exercise helps lose weight. The researchers discovered a mechanism by which the compound Lac-Phe, which is produced during exercise, reduces appetite in mice, leading to weight loss. The findings appeared in Nature