By Hugo Francisco de Souza Reviewed by Susha Cheriyedath, M.Sc. Apr 30 2026 By mapping CAR-T cells one by one, researchers are uncovering the cellular traits that may separate durable cancer responses from relapse. Review: Mapping clinical CAR-T cells: insights from scRNA-seq . Image Credit: Nemes Laszlo / Shutterstock In a recent review published in the journal  Trends in Molecular Medicine , researchers in the United States synthesized findings from single-cell RNA sequencing ( scRNA-seq ; n =