ChronODE method offers precision in timing gene therapy treatments
DNA
Yale University Aug 20 2025 A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off over time during brain development - a finding that may one day help doctors identify the optimal window to deploy gene therapy treatments. Dubbed "chronODE," the tool uses math and machine learning to model how gene activity and chromatin (the DNA and protein mix that forms chromosomes) patterns change over time. The tool may offer a variety of applications in
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