Methylation clocks may mislead anti-aging therapy evaluation
DNA
Aging-US Jun 10 2025 A new research perspective was published in Aging ( Aging-US ) Volume 17, Issue 5, on May 5, 2025, titled "Methylation clocks for evaluation of anti-aging interventions." In this perspective article, Dr. Josh Mitteldorf explores how current epigenetic clocks-used to estimate biological age-might mislead scientists trying to evaluate anti-aging therapies. The paper challenges a widespread assumption: that all changes in DNA methylation with age are equally valid for
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