Xia & He Publishing Inc. Feb 10 2026 Inherited hyperbilirubinemia, encompassing Gilbert syndrome, Crigler-Najjar syndrome, Dubin-Johnson syndrome, and Rotor syndrome, represents a spectrum of disorders rooted in genetic defects affecting bilirubin metabolism and transport. The recent 2025 Expert Consensus provides a crucial framework for standardizing the diagnosis and management of these conditions. A key strength of the consensus is its clear stratification of diseases based on the underlying